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Interleukin 17a antibody (Center)

IL17A Reactivity: Human, Mouse WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499980
  • Target See all Interleukin 17a (IL17A) Antibodies
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Binding Specificity
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reactivity
    • 90
    • 42
    • 19
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    Human, Mouse
    Host
    • 62
    • 40
    • 17
    • 7
    • 3
    Rabbit
    Clonality
    • 71
    • 57
    • 1
    Polyclonal
    Conjugate
    • 63
    • 21
    • 15
    • 10
    • 8
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Interleukin 17a antibody is un-conjugated
    Application
    • 71
    • 61
    • 31
    • 14
    • 11
    • 11
    • 10
    • 10
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to IL-17.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    IL-17 antibody was raised against a 19 amino acid peptide from near the center of human IL-17A.
    Isotype
    IgG
    Top Product
    Discover our top product IL17A Primary Antibody
  • Application Notes
    ELISA. Western Blot: 0.5 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
    Alternative Name
    Interleukin-17A (IL17A) (IL17A Products)
    Synonyms
    CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
    Background
    Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-kB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.Synonyms: CTLA-8, CTLA8, Cytotoxic T-lymphocyte-associated antigen 8, IL-17, IL-17A, IL17
    Gene ID
    3605
    NCBI Accession
    NP_002181
    UniProt
    Q16552
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