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IL22 Receptor alpha 1 antibody (N-Term)

IL22RA1 Reactivity: Human, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499994
  • Target See all IL22 Receptor alpha 1 (IL22RA1) Antibodies
    IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))
    Binding Specificity
    • 14
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 64
    • 28
    • 27
    • 9
    • 8
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Rat
    Host
    • 58
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 61
    • 4
    Polyclonal
    Conjugate
    • 31
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL22 Receptor alpha 1 antibody is un-conjugated
    Application
    • 57
    • 27
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    IL-22 receptor antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human IL-22 receptor precursor.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    Human IL-22 Receptor (N-Terminus) Peptide
    Isotype
    IgG
    Top Product
    Discover our top product IL22RA1 Primary Antibody
  • Application Notes
    ELISA. Western Blot: 0.5 to 1 μg/mL. An approximately 62 kDa band can be detected. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))
    Alternative Name
    IL22RA1 / IL22R (IL22RA1 Products)
    Synonyms
    IL22RA1 antibody, CRF2-9 antibody, IL22R antibody, IL22R1 antibody, 9130219A07Rik antibody, ENSMUSG00000073746 antibody, IL-22R antibody, Il22r antibody, RGD1559655 antibody, interleukin 22 receptor subunit alpha 1 antibody, interleukin 22 receptor, alpha 1 antibody, IL22RA1 antibody, Il22ra1 antibody
    Background
    A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified (1-3). The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family (3,4). IL-22R forms a complex with IL-10 receptor b chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-a 2 (IL-22RA2), was identified very recently (5-7). IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.Synonyms: CRF2-9, Cytokine receptor class-II member 9, Cytokine receptor family 2 member 9, IL-22 receptor subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Interleukin-22 receptor subunit alpha-1, ZcytoR11
    Gene ID
    58985
    UniProt
    Q8N6P7
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