INCA1 antibody (C-Term)

Catalog No. ABIN500026

This Rabbit Polyclonal antibody specifically detects INCA1 in WB and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for INCA1 antibody (C-Term) (ABIN500026)

Target: INCA1 (Inhibitor of CDK, Cyclin A1 Interacting Protein 1 (INCA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INCA1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-INCA1 Antibody

Binding Specificity: C-Term

Purification: Affinity chromatography purified via peptide column

Immunogen: INCA1 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human INCA1.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for INCA1

Target: INCA1 (Inhibitor of CDK, Cyclin A1 Interacting Protein 1 (INCA1))

Alternative Name: INCA1 / HSD45

Background: INCA1 was isolated through a yeast triple hybrid approach to identify interaction partners of the cyclin A1-CDK2 heterodimer. INCA1 is evolutionarily conserved and has no homology to any known proteins. Like Cyclin A1, INCA1 is highly expressed in testis with highest levels observed at various points of testis maturation. It has been suggested that the complex of INCA1 and the cyclinA1-CDK2 dimer plays a role in several signaling pathways important for cell cycle control and meiosis. Recent experiments have shown that INCA1 also interacts with the testis protein RSB-66 and this interaction takes place in the cytoplasm.Synonyms: Inhibitor of CDK1 interacting with cyclin A1

Gene ID: 388324

NCBI Accession: NP_998891

UniProt: Q0VD86