NIPSNAP1 antibody (Center)

Catalog No. ABIN500351

The Rabbit Polyclonal anti-NIPSNAP1 antibody is suitable to detect NIPSNAP1 in samples from Mouse, Human and Rat. It has been validated for WB, IHC (p) and EIA.

Quick Overview for NIPSNAP1 antibody (Center) (ABIN500351)

Target: NIPSNAP1 (4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (NIPSNAP1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NIPSNAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-NIPSNAP1 Antibody

Binding Specificity: Center

Specificity: This antibody detects NipSnap1 at center.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: NIPSNAP antibody was raised against a 19 amino acid peptide from near the center of human NIPSNAP.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for NIPSNAP1

Target: NIPSNAP1 (4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like Protein Homolog 1 (NIPSNAP1))

Alternative Name: NipSnap1

Background: NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.Synonyms: Protein NipSnap homolog 1

Gene ID: 8508

NCBI Accession: NP_003625

UniProt: Q9BPW8