NIPSNAP3A antibody (Center)
Quick Overview for NIPSNAP3A antibody (Center) (ABIN500357)
Target
See all NIPSNAP3A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Center
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Specificity
- This antibody detects NipSnap3A / NipSnap4. It is predicted to not cross-react with any other members of the NIPSNAP protein family.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse
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Purification
- Peptide affinity chromatography
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Immunogen
- NIPSNAP3A antibody was raised against a 16 amino acid peptide near the center of human NIPSNAP3A.
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Isotype
- IgG
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Application Notes
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ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- NIPSNAP3A (Nipsnap Homolog 3A (NIPSNAP3A))
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Alternative Name
- NipSnap3A / NipSnap4
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Background
- The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40 % of glioblastomas, the most common and malignant form of central nervous system tumors. While NIPSNAP3B is highly expressed skeletal muscle, NIPSNAP3A mRNA levels are low. NIPSNAP3A protein is associated with plasma membrane and partially localized in rafts. NIPSNAP proteins have been suggested to be important in vesicular transport. At least two isoforms of NIPSNAP3A are known to exist.Synonyms: Protein NipSnap homolog 3A
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Gene ID
- 25934
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NCBI Accession
- NP_056284
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UniProt
- Q9UFN0
Target
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