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PDCD5 antibody (N-Term)

PDCD5 Reactivity: Human, Mouse, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN500465
  • Target See all PDCD5 Antibodies
    PDCD5 (Programmed Cell Death 5 (PDCD5))
    Binding Specificity
    • 15
    • 9
    • 9
    • 7
    • 7
    • 5
    • 4
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat
    Host
    • 54
    • 2
    Rabbit
    Clonality
    • 54
    • 1
    Polyclonal
    Conjugate
    • 20
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDCD5 antibody is un-conjugated
    Application
    • 39
    • 22
    • 13
    • 13
    • 9
    • 9
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects PDCD5 at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Peptide affinity chromatography
    Immunogen
    PDCD5 antibody was raised against a 13 amino acid peptide from near the amino terminus of human PDCD5.
    Isotype
    IgG
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    Discover our top product PDCD5 Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    PDCD5 (Programmed Cell Death 5 (PDCD5))
    Alternative Name
    PDCD5 (PDCD5 Products)
    Synonyms
    zgc:56315 antibody, tfar19 antibody, DKFZp468P187 antibody, TFAR19 antibody, 2200003D22Rik antibody, AA408513 antibody, Tfar19 antibody, programmed cell death 5 antibody, programmed cell death 5 S homeolog antibody, DNA-binding protein antibody, pdcd5 antibody, PDCD5 antibody, pdcd5.S antibody, SSO_RS01750 antibody, Pdcd5 antibody
    Background
    Programmed cell death 5 (PDCD5), a human apoptosis-related protein, is thought to play an early and universal role in apoptosis. PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis, where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 has a compact core structure of low flexibility with two mobile alpha-helices at N-terminal and a flexible unstructured C-terminal region. The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein. PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death. PDCD5 may play a dual role in the Tip60 pathway. It interacts with Tip60 and functions as a Tip60 co-activator to promote apoptosis (5). The nucleotide polymorphisms in the 5?-upstream region of PDCD5 affect promoter activity and the susceptibility of a Chinese population to develop chronic myelogenous leukemia and may represent a novel tumor suppressor gene influencing lung cancer.Synonyms: Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, TFAR19
    Gene ID
    9141
    NCBI Accession
    NP_004699
    UniProt
    O14737
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