THEM2 antibody (C-Term)

Catalog No. ABIN500903

The Rabbit Polyclonal anti-THEM2 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect THEM2 in samples from Human, Rat and Mouse.

Quick Overview for THEM2 antibody (C-Term) (ABIN500903)

Target: THEM2 (ACOT13) (Acyl-CoA Thioesterase 13 (ACOT13))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THEM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-THEM2 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects THEM2 / ACOT13.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Peptide affinity chromatography

Immunogen: THEM2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THEM2.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for THEM2

Target: THEM2 (ACOT13) (Acyl-CoA Thioesterase 13 (ACOT13))

Alternative Name: THEM2 / ACOT13

Background: THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.Synonyms: Acyl-CoA thioesterase 13, Acyl-coenzyme A thioesterase 13, HT012, PNAS-27, Thioesterase superfamily member 2

Gene ID: 55856

NCBI Accession: NP_060943