THEM2 antibody (C-Term)

Catalog No. ABIN6991152

The Rabbit Polyclonal anti-THEM2 antibody (ABIN6991152) specifically detects THEM2 in WB, ELISA, IHC (p) and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for THEM2 antibody (C-Term) (ABIN6991152)

Target: THEM2 (ACOT13) (Acyl-CoA Thioesterase 13 (ACOT13))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THEM2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details anti-THEM2 Antibody

Binding Specificity: C-Term

Purification: THEM2 Antibody is affinity chromatography purified via peptide column.

Immunogen: THEM2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human THEM2. The immunogen is located within the last 50 amino acids of THEM2.

Isotype: IgG

Application Details

Application Notes: THEM2 antibody can be used for detection of THEM2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: THEM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,4 °C

Storage Comment: THEM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for THEM2

Target: THEM2 (ACOT13) (Acyl-CoA Thioesterase 13 (ACOT13))

Alternative Name: THEM2

Background: THEM2 Antibody: THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.

Gene ID: 55856

NCBI Accession: NP_060943

UniProt: Q9NPJ3