ZC3H12B antibody (N-Term)

Catalog No. ABIN501153

The Rabbit Polyclonal anti-ZC3H12B antibody (ABIN501153) specifically detects ZC3H12B in WB, IHC (p) and EIA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ZC3H12B antibody (N-Term) (ABIN501153)

Target: ZC3H12B (Zinc Finger CCCH-Type Containing 12B (ZC3H12B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC3H12B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-ZC3H12B Antibody

Binding Specificity: N-Term

Specificity: This antibody detects ZC3H12B.

Purification: Affinity chromatography

Immunogen: ZC3H12B antibody was raised against a 17 amino acid peptide near the amino terminus of human ZC3H12B.

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ZC3H12B

Target: ZC3H12B (Zinc Finger CCCH-Type Containing 12B (ZC3H12B))

Alternative Name: ZC3H12B

Background: ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).Synonyms: CXorf32, MCP-induced protein 2, MCPIP2, Probable ribonuclease ZC3H12B, Zinc finger CCCH domain-containing protein 12B

Gene ID: 340554

NCBI Accession: NP_001010888