Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8) (Middle Region) antibody

Details for Product No. ABIN501376
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Antigen
Synonyms kir6.1, KIR6.1, uKATP-1, AI448900, Kir6.1, gnite, slmbr, sltr, UKATP1, si:dkey-183c2.2, zkir6.1
Epitope
Middle Region
(10), (8), (4), (2), (2), (1)
Reactivity
Rabbit, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Cow (Bovine), Xenopus laevis, Dog (Canine), Pig (Porcine), Human
(37), (25), (25), (17), (17), (17)
Host
Rabbit
(36), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(23), (14), (13), (10), (6), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN501376
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human KCNJ8
Sequence EKPSILIQTL QKSELSHQNS LRKRNSMRRN NSMRRNNSIR RNNSSLMVPK
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Zebrafish : 100 %
Characteristics This is a rabbit polyclonal antibody against KCNJ8. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name KCNJ8
Background Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. KCNJ8 is an integral membrane protein and inward-rectifier type potassium channel. KCNJ8, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins.
Molecular Weight 48 kDa
Gene ID 3764
NCBI Accession NP_004973, NM_004982
UniProt Q15842
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 424 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8) (Middle Region) antibody WB Suggested Anti-KCNJ8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Hela cell lysate
Background publications Ji, Foo, ORoak et al.: "Rare independent mutations in renal salt handling genes contribute to blood pressure variation." in: Nature genetics, Vol. 40, Issue 5, pp. 592-9, 2008 (PubMed).

Validation Images
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