TPCN1 antibody (N-Term)

Catalog No. ABIN501390

The Rabbit Polyclonal anti-TPCN1 antibody (ABIN501390) specifically detects TPCN1 in WB. The antibody is reactive with Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for TPCN1 antibody (N-Term) (ABIN501390)

Target: TPCN1 (Two Pore Segment Channel 1 (TPCN1))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPCN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TPCN1 Antibody

Binding Specificity: N-Term

Purpose: TPCN1 Antibody - N-terminal region

Sequence: YQEAAIYLQE GENNDKFFTH PKDAKALAAY LFAHNHLFYL MELATALLLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TPCN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TPCN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35276-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TPCN1

Target: TPCN1 (Two Pore Segment Channel 1 (TPCN1))

Alternative Name: TPCN1

Background:

Background Information: TPCN1 may function as one of the major voltage-gated Ca2+ channel (VDCC) across the plasma membrane.Voltage-gated Ca(2+) and Na+ channels have 4 homologous domains, each containing 6 transmembrane segments, S1 to S6. TPCN1 is similar to these channels, but it has only 2 domains containing S1 to S6 (Ishibashi et al., 2000 [PubMed 10753632]).[supplied by OMIM].

Gene Name: Two pore segment channel 1

Alternative Symbols: TPC1

Protein Name: Two pore calcium channel protein 1

Molecular Weight: 94 kDa

Gene ID: 53373

NCBI Accession: NP_060371

UniProt: Q9ULQ1