TCEB3B antibody (Middle Region)

Catalog No. ABIN501480

The Rabbit Polyclonal anti-TCEB3B antibody (ABIN501480) specifically detects TCEB3B in WB. The antibody is reactive with Human samples.

Quick Overview for TCEB3B antibody (Middle Region) (ABIN501480)

Target: TCEB3B (Transcription Elongation Factor B Polypeptide 3B (Elongin A2) (TCEB3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCEB3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TCEB3B Antibody

Binding Specificity: Middle Region

Purpose: ELOA2 Antibody - middle region

Sequence: QAGSGQRVPA LEEAPDSHQK RPQHSHSNKK RPSLDGRDPG NGTHGLSPEE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against TCEB3B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TCEB3B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP35916-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCEB3B

Target: TCEB3B (Transcription Elongation Factor B Polypeptide 3B (Elongin A2) (TCEB3B))

Alternative Name: ELOA2

Background:

Targeted Subunit: A2

Background Information: This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis.

Gene Name: elongin A2

Alternative Symbols: HsT832, TCEB3B, TCEB3L

Protein Name: elongin-A2

Molecular Weight: 84kDa

Gene ID: 51224

NCBI Accession: NP_057511

UniProt: Q8IYF1