Gap Junction Protein, beta 6, 30kDa (GJB6) (Middle Region) antibody

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Antigen
Synonyms connexin-26, cx26, cx30, dfna3, dfna3a, dfnb1, dfnb1a, ed2, edh, gjb6, hed, nsrd1, ppk, AA958971, Cx30, D14Bwg0506e, CX30, DFNA3, DFNA3B, DFNB1B, ECTD2, ED2, EDH, HED, HED2, CX31
Epitope
Middle Region
(20), (6), (2), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(46), (11), (11), (3), (1)
Host
Rabbit
(34), (13), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (3), (3), (3), (1)
Application
Western Blotting (WB)
(35), (31), (23), (3), (1), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human GJB6
Blocking Peptide Blocking peptide for this product available: Gap Junction Protein, beta 6, 30kDa (GJB6) (Middle Region) peptide (ABIN977429)
Sequence CYLLLKVCFR RSKRAQTQKN HPNHALKESK QNEMNELISD SGQNAITGFP
Predicted Reactivity Mouse : 92 %, Rat : 92 %, Goat : 72 %
Characteristics This is a rabbit polyclonal antibody against GJB6. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name GJB6 (GJB6 Antibody Abstract)
Background Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extrac
Molecular Weight 30 kDa
Gene ID 10804
NCBI Accession NM_006783, NP_006774
UniProt O95452
Research Area Neurology
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 261 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Gap Junction Protein, beta 6, 30kDa (GJB6) (Middle Region) antibody (ABIN501574) WB Suggested Anti-GJB6 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Background publications BuSaba, Cunningham: "Connexin 26 and 30 genes mutations in patients with chronic rhinosinusitis." in: The Laryngoscope, Vol. 118, Issue 2, pp. 310-3, 2008 (PubMed).

Catalog No. ABIN501574
$289.00
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