GJB6 Products
(Gap Junction Protein, beta 6, 30kDa (GJB6))
Categories
Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. [provided by RefSeq, Jul 2008].
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Featured GJB6 Categories
GJB6 Antibodies
High quality antibodies with extensive validation data.
GJB6 ELISA Kits
Reliable ELISA kits for a wide range of species.
GJB6 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended GJB6 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (3)
Cat. No.
ABIN544549
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC, WB
Validations
- (3)
Cat. No.
ABIN7000954
Quantity
20 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7153625
Quantity
100 μg
Datasheet
Datasheet
Recommended GJB6 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956054
Quantity
96 tests
Datasheet
Datasheet
Recommended GJB6 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1355149
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3111248
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
Cat. No.
ABIN3121036
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our GJB6 products
: "Expressional and functional involvement of gap junctions in aqueous humor outflow into the ocular trabecular meshwork of the anterior chamber." in: Molecular vision, Vol. 25, pp. 255-265, (2019) (PubMed).: "HIV-tat alters Connexin43 expression and trafficking in human astrocytes: role in NeuroAIDS." in: Journal of neuroinflammation, Vol. 13, Issue 1, pp. 54, (2016) (PubMed).
: "Mutation in gap and tight junctions in patients with non-syndromic hearing loss." in: Biochemical and biophysical research communications, Vol. 385, Issue 1, pp. 1-5, (2009) (PubMed).
: "Permeability and gating properties of human connexins 26 and 30 expressed in HeLa cells." in: Biochemical and biophysical research communications, Vol. 305, Issue 4, pp. 1024-33, (2003) (PubMed).
: "Functional studies of human skin disease- and deafness-associated connexin 30 mutations." in: Biochemical and biophysical research communications, Vol. 298, Issue 5, pp. 651-6, (2002) (PubMed).
: "A novel connexin 30 mutation in Clouston syndrome." in: The Journal of investigative dermatology, Vol. 118, Issue 3, pp. 530-2, (2002) (PubMed).
Synonyms and alternative names related to GJB6
connexin 30 (LOC387566), gap junction protein beta 2 (gjb2), gap junction protein beta 6 (GJB6), gap junction protein, beta 6 (Gjb6), AA958971, connexin-26, cx26, cx30, Cx30, CX30, CX31, D14Bwg0506e, dfna3, DFNA3, dfna3a, DFNA3B, dfnb1, dfnb1a, DFNB1B, ECTD2, ed2, ED2, edh, EDH, gjb6, hed, HED, HED2, nsrd1, ppkProtein level used designations for GJB6
- connexin 30
- connexin 26
- gap junction beta-2 protein
- gap junction protein, beta 6, 30kDa
- connexin-30
- gap junction beta-6 protein
- gap junction membrane channel protein beta 6
- gap junction protein, beta 6 (connexin 30)
- ectodermal dysplasia 2, hidrotic (Clouston syndrome)
- connexin 31
- connexin-31
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