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GJB6 antibody

GJB6 Reactivity: Human, Mouse ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7000954
  • Target See all GJB6 Antibodies
    GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))
    Reactivity
    • 29
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 27
    • 1
    • 1
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GJB6 antibody is un-conjugated
    Application
    • 16
    • 15
    • 12
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Synthetic peptide of human GJB6
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:25-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.3 mg/mL
    Buffer
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))
    Alternative Name
    GJB6 (GJB6 Products)
    Synonyms
    connexin-26 antibody, cx26 antibody, cx30 antibody, dfna3 antibody, dfna3a antibody, dfnb1 antibody, dfnb1a antibody, ed2 antibody, edh antibody, gjb6 antibody, hed antibody, nsrd1 antibody, ppk antibody, AA958971 antibody, Cx30 antibody, D14Bwg0506e antibody, CX30 antibody, DFNA3 antibody, DFNA3B antibody, DFNB1B antibody, ECTD2 antibody, ED2 antibody, EDH antibody, HED antibody, HED2 antibody, CX31 antibody, connexin 30 antibody, gap junction protein beta 2 antibody, gap junction protein beta 6 antibody, gap junction protein, beta 6 antibody, LOC387566 antibody, gjb2 antibody, GJB6 antibody, Gjb6 antibody
    Background
    Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia.
    Molecular Weight
    30 kDa
    NCBI Accession
    NP_006774
    UniProt
    O95452
    Pathways
    Sensory Perception of Sound
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