CRLF1 antibody (Middle Region)

Catalog No. ABIN501581

The Rabbit Polyclonal anti-CRLF1 antibody has been validated for WB. It is suitable to detect CRLF1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for CRLF1 antibody (Middle Region) (ABIN501581)

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLF1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRLF1 Antibody

Binding Specificity: Middle Region

Sequence: QLSVRWVSPP ALKDFLFQAK YQIRYRVEDS VDWKVVDDVS NQTSCRLAGL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CRLF1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CRLF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 422 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRLF1

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Alternative Name: CRLF1

Background: CRLF1 belongs to the type I cytokine receptor family. It is cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. The protein may be involved in nervous system development.Defects in CRLF1 are the cause of cold-induced sweating syndrome 1 and Crisponi syndrome.
Alias Symbols: CISS, CISS1, CLF, CLF-1, NR6, zcytor5
Protein Interaction Partner: CLCF1, CNTFR,
Protein Size: 422

Molecular Weight: 46 kDa

Gene ID: 9244

NCBI Accession: NM_004750, NP_004741

UniProt: O75462