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Antibodies
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anti-Single-Minded Homolog 2 (Drosophila) (SIM2) antibody
Single-Minded Homolog 2 (Drosophila) (SIM2) antibody
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| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish, Dog (Canine), Chicken, Pig (Porcine), Fruit Fly (Drosophila melanogaster)
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Application
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| Catalog no. |
ABIN501700 |
| Quantity |
50 µg |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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SIM2
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Gene ID
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SIM2
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UniProt
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Q14190
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Immunogen
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The immunogen for anti-SIM2 antibody: synthetic peptide directed towards the N terminal of human SIM2
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Sequence
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MKEKSKNAAKTRREKENGEFYELAKLLPLPSAITSQLDKA SIIRLTTSYL
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Cross-Reactivity
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Cow (Bovine), Dog (Canine), Chicken, Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-SIM2 antibody concentration is 1 mg/ml.
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Description
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SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. The Drosophila sim gene encodes a transcription factor that is a master regulator of fruit fly neurogenesis. SIM2 maps within the so-called Down syndrome chromosomal region. Based on t
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Characteristics
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Antigen Size: 667 amino acids
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Molecular Weight
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73kDa
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Application Notes
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WB Suggested Anti-SIM2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human kidney.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Laffin, Wellberg, Kwak et al.: "Loss of singleminded-2s in the mouse mammary gland induces an epithelial-mesenchymal transition associated with up-regulation of slug and matrix metalloprotease 2." in: Molecular and cellular biology, Vol. 28, Issue 6, pp. 1936-46, 2008 (PubMed).
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Alternatives for antigen "Single-Minded Homolog 2 (Drosophila) (SIM2)", type "Antibodies"
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Hosts
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Rabbit (26), Goat (3), Mouse (3)
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Reactivities
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Human (30), Mouse (Murine) (23), Rat (Rattus) (22)
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Applications
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Immunofluorescence (IF) (16), Western Blotting (WB) (15), ELISA (13), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Epitopes
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AA 372-384 (1), AA 426-526 (1), Internal Region (1), N-Term (1)
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