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SIM2 antibody (N-Term)

SIM2 Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Cow, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780639
  • Target See all SIM2 Antibodies
    SIM2 (Single-Minded Homolog 2 (SIM2))
    Binding Specificity
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 29
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Cow, Zebrafish (Danio rerio)
    Host
    • 26
    • 3
    • 1
    Rabbit
    Clonality
    • 28
    • 2
    Polyclonal
    Conjugate
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIM2 antibody is un-conjugated
    Application
    • 13
    • 13
    • 13
    • 10
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    MKEKSKNAAK TRREKENGEF YELAKLLPLP SAITSQLDKA SIIRLTTSYL
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SIM2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SIM2
    Top Product
    Discover our top product SIM2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 667 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

  • Target
    SIM2 (Single-Minded Homolog 2 (SIM2))
    Alternative Name
    SIM2 (SIM2 Products)
    Synonyms
    Xsim2 antibody, sim2-A antibody, xSim antibody, HMC13F06 antibody, HMC29C01 antibody, SIM antibody, bHLHe15 antibody, single-minded family bHLH transcription factor 2 S homeolog antibody, single-minded family bHLH transcription factor 2 antibody, single-minded homolog 2 (Drosophila) antibody, sim2.S antibody, sim2 antibody, SIM2 antibody, Sim2 antibody
    Background
    SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. The Drosophila sim gene encodes a transcription factor that is a master regulator of fruit fly neurogenesis. SIM2 maps within the so-called Down syndrome chromosomal region. Based on t
    Alias Symbols: MGC119447, SIM, bHLHe15, HMC13F06, HMC29C01
    Protein Interaction Partner: Dlg4, HSP90AA1, ARIH1, UBC, PARK2, ARNT, ARNT2, EPO,
    Protein Size: 667
    Molecular Weight
    73 kDa
    Gene ID
    6493
    NCBI Accession
    NM_005069, NP_005060
    UniProt
    Q14190
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