ZNF446 antibody (N-Term)

Catalog No. ABIN501799

This Rabbit Polyclonal antibody specifically detects ZNF446 in WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ZNF446 antibody (N-Term) (ABIN501799)

Target: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF446 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZNF446 Antibody

Binding Specificity: N-Term

Purpose: ZNF446 Antibody - N-terminal region

Sequence: MPSPLGPPCL PVMDPETTLE EPETARLRFR GFCYQEVAGP REALARLREL

Predicted Reactivity: Human: 100%, Mouse: 90%, Rat: 90%

Characteristics: This is a rabbit polyclonal antibody against ZNF446. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF446

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39318-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF446

Target: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Alternative Name: ZNF446

Background:

Background Information: ZNF446 contains a KRAB and three C(2)H(2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-

Gene Name: Zinc finger protein 446

Alternative Symbols: ZSCAN30, ZSCAN52, ZKSCAN20

Protein Name: Zinc finger protein 446

Molecular Weight: 49kDa

Gene ID: 55663

NCBI Accession: NP_060378

UniProt: Q9NWS9