Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4) antibody

Antigen: Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4)

Synonyms: p12, YHHQ1, 2400007P05Rik, 5830430F06Rik, POLE4, pole4

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Human, Dog (Canine)

Application: Western Blotting (WB)

Catalog no.: ABIN501810

Additional Information

Alternative name: POLE4

Gene ID: POLE4

UniProt: Q9NR33

Immunogen: The immunogen for anti-POLE4 antibody: synthetic peptide directed towards the N terminal of human POLE4

Sequence: MAAAAAAGSGTPREEEGPAGEAAASQPQAPTSVPGARLSR LPLARVKALV

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human

Format: Lyophilized

Reconstitution: Add 50 µl of distilled water. Final anti-POLE4 antibody concentration is 1 mg/ml.

Description: POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.

Characteristics: Antigen Size: 117 amino acids

Molecular Weight: 12kDa

Application Details

Application Notes: WB Suggested Anti-POLE4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysate.

Purification: Affinity Purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

WB Suggested Anti-POLE4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysate

Publications

Product: Hillier, Graves, Fulton et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).