FOXM1 antibody (Middle Region)

Catalog No. ABIN501829

This Rabbit Polyclonal antibody specifically detects FOXM1 in WB. It exhibits reactivity toward Human, Rat, Mouse, Dog, Rabbit and Guinea Pigand has been mentioned in 1 publication.

Quick Overview for FOXM1 antibody (Middle Region) (ABIN501829)

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXM1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FOXM1 Antibody

Binding Specificity: Middle Region

Sequence: ANRSLTEGLV LDTMNDSLSK ILLDISFPGL DEDPLGPDNI NWSQFIPELQ

Predicted Reactivity: Dog: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FOXM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXM1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 763 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FOXM1 antibody (ABIN501829)

Hu, Liu, Zhang, Lou, Huang, Chen, Shen, Gao, Gong, Zhou, Dai, Zeng, He: "LXR?-mediated downregulation of FOXM1 suppresses the proliferation of hepatocellular carcinoma cells." in: Oncogene, Vol. 33, Issue 22, pp. 2888-97, (2014) (PubMed).

Target Details for FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Alternative Name: FOXM1

Background: This protein acts as a Transcriptional activatory factor. May play a role in the control of cell proliferation.
Alias Symbols: FKHL16, FOXM1B, HFH-11, HFH11, HNF-3, INS-1, MPHOSPH2, MPP-2, MPP2, PIG29, TGT3, TRIDENT
Protein Interaction Partner: SMAD3, FZR1, SUMO1, UBE2I, SP1, CDK2, CCNE1, BANP, OS9, HSP90AA1, CDK6, CDK4, DHX29, ACAT1, CDC27, UBC, BCL6, SUMO2, RB1, CREBBP, CDC25B, CDK1, CCNB1, ZBTB3, CHEK2, STAT3, CDH1, CENPF,
Protein Size: 763

Molecular Weight: 84 kDa

Gene ID: 2305

NCBI Accession: NM_021953, NP_068772

UniProt: Q08050

Pathways: Positive Regulation of Response to DNA Damage Stimulus