SOX7 antibody (Middle Region)

Catalog No. ABIN501857

The Rabbit Polyclonal anti-SOX7 antibody has been validated for WB and IHC. It is suitable to detect SOX7 in samples from Human, Mouse, Rat, Cow, Rabbit, Guinea Pig and Dog.

Quick Overview for SOX7 antibody (Middle Region) (ABIN501857)

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SOX7 Antibody

Binding Specificity: Middle Region

Sequence: LLGDMDRNEF DQYLNTPGHP DSATGAMALS GHVPVSQVTP TGPTETSLIS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SOX7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 388 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SOX7

Target: SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))

Alternative Name: SOX7

Background: SOX7 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. SOX7 may act as a transcriptional regulator after forming a protein complex with other proteins. It may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may play a role in tumorigenesis. A similar protein in mice is involved in the regulation of the wingless-type MMTV integration site family (Wnt) pathway.
Alias Symbols: MGC10895
Protein Interaction Partner: GLRX3, Dlg4, SMAD7, SMAD5, APP,
Protein Size: 388

Molecular Weight: 42 kDa

Gene ID: 83595

NCBI Accession: NM_031439, NP_113627

UniProt: Q9BT81

Pathways: Positive Regulation of Endopeptidase Activity