SOX7 antibody (AA 224-258)
Quick Overview for SOX7 antibody (AA 224-258) (ABIN6244006)
Target
See all SOX7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 224-258
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This SOX7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 224-258 amino acids from the Central region of human SOX7.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- SOX7 (SRY (Sex Determining Region Y)-Box 7 (SOX7))
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Alternative Name
- SOX7
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Background
- Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.
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Molecular Weight
- 42197
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UniProt
- Q9BT81
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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