F12 antibody (N-Term)

Catalog No. ABIN502168

This Rabbit Polyclonal antibody specifically detects F12 in WB. It exhibits reactivity toward Human.

Quick Overview for F12 antibody (N-Term) (ABIN502168)

Target: F12 (Coagulation Factor XII (F12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-F12 Antibody

Binding Specificity: N-Term

Sequence: MRALLLLGFL LVSLESTLSI PPWEAPKEHK YKAEEHTVVL TVTGEPCHFP

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against F12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human F12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 615 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for F12

Target: F12 (Coagulation Factor XII (F12))

Alternative Name: F12

Background: This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type
Alias Symbols: HAE3, HAEX, HAF
Protein Interaction Partner: UBE2D3, UBE2D2, UBE2D1, UBC, HIF1A, UBE2N, UBE2E1, EPAS1, MMP12, MMP14, MMP13, GP1BA, KLKB1, KRT1, APOH, CD93, APP,
Protein Size: 615

Molecular Weight: 26 kDa

Gene ID: 2161

NCBI Accession: NM_000505, NP_000496

UniProt: P00748

Pathways: Complement System