DLG3 antibody (Middle Region)

Catalog No. ABIN502417

This Rabbit Polyclonal antibody specifically detects DLG3 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse and Zebrafish (Danio rerio).It has been mentioned in 1 publication

Quick Overview for DLG3 antibody (Middle Region) (ABIN502417)

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DLG3 Antibody

Binding Specificity: Middle Region

Sequence: FPHKFGSCVP HTTRPRRDNE VDGQDYHFVV SREQMEKDIQ DNKFIEAGQF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DLG3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DLG3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 817 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DLG3 antibody (ABIN502417)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for DLG3

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Alternative Name: DLG3

Background: DLG3 is required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling. Defects in DLG3 are the cause of mental retardation X-linked type 90 (MRX90).
Alias Symbols: KIAA1232, MRX, MRX90, NE-Dlg, NEDLG, SAP102, XLMR
Protein Interaction Partner: UBC, BAG3, PPP1CA, KHDRBS1, ELAVL1, DLGAP3, DLGAP4, SYNGAP1, GRIN1, LPHN1, EXOC4, KCNJ12, GDA, SEMA4C, CNKSR2, GLS2, KIF1B, CRIPT, SCN4A, LIN7A, CACNG2, DLG4, MAPK12, GUCY1A2, PTK2B, DLG1, KCNJ2, ERBB4, SCN5A, LRP2, ABCA1, NLGN3, KCNA4, GRIN2C, GRIN2A, GR
Protein Size: 817

Molecular Weight: 90 kDa

Gene ID: 1741

NCBI Accession: NM_021120, NP_066943

UniProt: Q92796