SLC25A11 antibody (C-Term)

Catalog No. ABIN502439

Product Details anti-SLC25A11 Antibody

Target: SLC25A11 (Solute Carrier Family 25 (Mitochondrial Carrier, Oxoglutarate Carrier), Member 11 (SLC25A11))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DGKPEYKNGL DVLFKVVRYE GFFSLWKGFT PYYARLGPHT VLTFIFLEQM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC25A11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC25A11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC25A11

Target: SLC25A11 (Solute Carrier Family 25 (Mitochondrial Carrier, Oxoglutarate Carrier), Member 11 (SLC25A11))

Alternative Name: SLC25A11 (SLC25A11 Products)

Background: SLC25A11 catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.
Alias Symbols: OGC, SLC20A4
Protein Interaction Partner: RAPGEF2, UBC, SUMO2, STAU1, SUZ12, RNF2, BMI1, FBXO6, FBXO46, FBXW4, ADRB2, CLN5, CLN3, MMS19, UBL4A, MDC1, ECT2, FLOT1, HDAC5, MYC, ICT1, CEBPA, CAMKK2, BABAM1, SLC25A11, COPA, CDKN1A,
Protein Size: 314

Molecular Weight: 34 kDa

Gene ID: 8402

NCBI Accession: NM_003562, NP_003553

UniProt: Q02978

Pathways: Dicarboxylic Acid Transport