SLC25A11 antibody (C-Term)

Catalog No. ABIN502439

The Rabbit Polyclonal anti-SLC25A11 antibody has been validated for WB and IHC. It is suitable to detect SLC25A11 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio) and Horse.

Quick Overview for SLC25A11 antibody (C-Term) (ABIN502439)

Target: SLC25A11 (Solute Carrier Family 25 (Mitochondrial Carrier, Oxoglutarate Carrier), Member 11 (SLC25A11))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio), Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SLC25A11 Antibody

Binding Specificity: C-Term

Sequence: DGKPEYKNGL DVLFKVVRYE GFFSLWKGFT PYYARLGPHT VLTFIFLEQM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SLC25A11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SLC25A11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 314 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLC25A11

Target: SLC25A11 (Solute Carrier Family 25 (Mitochondrial Carrier, Oxoglutarate Carrier), Member 11 (SLC25A11))

Alternative Name: SLC25A11

Background: SLC25A11 catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.
Alias Symbols: OGC, SLC20A4
Protein Interaction Partner: RAPGEF2, UBC, SUMO2, STAU1, SUZ12, RNF2, BMI1, FBXO6, FBXO46, FBXW4, ADRB2, CLN5, CLN3, MMS19, UBL4A, MDC1, ECT2, FLOT1, HDAC5, MYC, ICT1, CEBPA, CAMKK2, BABAM1, SLC25A11, COPA, CDKN1A,
Protein Size: 314

Molecular Weight: 34 kDa

Gene ID: 8402

NCBI Accession: NM_003562, NP_003553

UniProt: Q02978

Pathways: Dicarboxylic Acid Transport