SC5DL antibody (N-Term)

Catalog No. ABIN502559

The Rabbit Polyclonal anti-SC5DL antibody is suitable to detect SC5DL in samples from Human. It has been validated for WB.

Quick Overview for SC5DL antibody (N-Term) (ABIN502559)

Target: SC5DL (Sterol-C5-Desaturase (SC5DL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SC5DL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SC5DL Antibody

Binding Specificity: N-Term

Purpose: SC5DL Antibody - N-terminal region

Sequence: NQVRREIKFT VQALPWISIL TVALFLLEIR GYSKLHDDLG EFPYGLFELV

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SC5DL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SC5DL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44751-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SC5DL

Target: SC5DL (Sterol-C5-Desaturase (SC5DL))

Alternative Name: SC5DL

Background:

Background Information: SC5DL catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol.This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described.

Gene Name: Sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like

Alternative Symbols: ERG3, S5DES, SC5DL

Protein Name: Lathosterol oxidase

Molecular Weight: 35kDa

Gene ID: 6309

NCBI Accession: NP_001020127

UniProt: O75845