LRRC8B antibody (Middle Region)

Catalog No. ABIN502806

This anti-LRRC8B antibody is a Rabbit Polyclonal antibody detecting LRRC8B in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit. This Primary Antibody has been cited in 1 publication.

Quick Overview for LRRC8B antibody (Middle Region) (ABIN502806)

Target: LRRC8B (Leucine Rich Repeat Containing 8 Family, Member B (LRRC8B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC8B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LRRC8B Antibody

Binding Specificity: Middle Region

Sequence: TLYLKSSLSR IPQVVTDLLP SLQKLSLDNE GSKLVVLNNL KKMVNLKSLE

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LRRC8B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LRRC8B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 803 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-LRRC8B antibody (ABIN502806)

Kubota, Kim, Sawada, Tokimasa, Fujisaki, Matsuda-Hashii, Ozono, Hara: "LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins." in: FEBS letters, Vol. 564, Issue 1-2, pp. 147-52, (2004) (PubMed).

Target Details for LRRC8B

Target: LRRC8B (Leucine Rich Repeat Containing 8 Family, Member B (LRRC8B))

Alternative Name: LRRC8B

Background: The exact function of LRRC8B remains unknown.
Alias Symbols: KIAA0231, MGC42220, TA-LRRP, TALRRP
Protein Interaction Partner: CUL3,
Protein Size: 803

Molecular Weight: 92 kDa

Gene ID: 23507

NCBI Accession: NM_015350, NP_056165

UniProt: Q6P9F7