CYP4F12 antibody (Middle Region)

Catalog No. ABIN503083

This Rabbit Polyclonal antibody specifically detects CYP4F12 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Rabbit and Pig.

Quick Overview for CYP4F12 antibody (Middle Region) (ABIN503083)

Target: CYP4F12 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 12 (CYP4F12))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP4F12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CYP4F12 Antibody

Binding Specificity: Middle Region

Purpose: CYP4F12 Antibody - middle region

Sequence: DGRRFHRACR LVHDFTDAVI RERRRTLPTQ GIDDFFKDKA KSKTLDFIDV

Predicted Reactivity: Cow: 79%, Human: 100%, Mouse: 85%, Pig: 79%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against CYP4F12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYP4F12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49788-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYP4F12

Target: CYP4F12 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 12 (CYP4F12))

Alternative Name: CYP4F12

Background:

Background Information: CYP4F12 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Tt likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid, however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid, however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19.

Gene Name: Cytochrome P450, family 4, subfamily F, polypeptide 12

Alternative Symbols: CYPIVF12, F22329_1

Protein Name: Cytochrome P450 4F12

Molecular Weight: 60kDa

Gene ID: 66002

NCBI Accession: NP_076433

UniProt: Q9HCS2

Pathways: Monocarboxylic Acid Catabolic Process