DIRAS1 antibody (Middle Region)

Catalog No. ABIN503386

This Rabbit Polyclonal antibody specifically detects DIRAS1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Pig, Horse, Cow and Zebrafish (Danio rerio).

Quick Overview for DIRAS1 antibody (Middle Region) (ABIN503386)

Target: DIRAS1 (DIRAS Family, GTP-Binding RAS-Like 1 (DIRAS1))

Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIRAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DIRAS1 Antibody

Binding Specificity: Middle Region

Sequence: KCAFMETSAK MNYNVKELFQ ELLTLETRRN MSLNIDGKRS GKQKRTDRVK

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 79%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against DIRAS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DIRAS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 198 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DIRAS1

Target: DIRAS1 (DIRAS Family, GTP-Binding RAS-Like 1 (DIRAS1))

Alternative Name: DIRAS1

Background: DIRAS1 belongs to a distinct branch of the functionally diverse Ras superfamily of monomeric GTPases. DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS, MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM]. Sequence Note: removed 1 base from the 5' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-3390 BC030660.1 2-3391
Alias Symbols: Di-Ras1, FLJ42681, GBTS1, RIG
Protein Interaction Partner: UBC, APP, Nedd4,
Protein Size: 198

Molecular Weight: 22 kDa

Gene ID: 148252

NCBI Accession: NM_145173, NP_660156

UniProt: O95057

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly