KHDRBS2 antibody (Middle Region)

Catalog No. ABIN503431

This Rabbit Polyclonal antibody specifically detects KHDRBS2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).It has been mentioned in 1 publication

Quick Overview for KHDRBS2 antibody (Middle Region) (ABIN503431)

Target: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KHDRBS2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KHDRBS2 Antibody

Binding Specificity: Middle Region

Sequence: EAYSRMSHAL EEIKKFLVPD YNDEIRQEQL RELSYLNGSE DSGRGRGIRG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against KHDRBS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KHDRBS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KHDRBS2 antibody (ABIN503431)

Stoss, Novoyatleva, Gencheva, Olbrich, Benderska, Stamm: "p59(fyn)-mediated phosphorylation regulates the activity of the tissue-specific splicing factor rSLM-1." in: Molecular and cellular neurosciences, Vol. 27, Issue 1, pp. 8-21, (2004) (PubMed).

Target Details for KHDRBS2

Target: KHDRBS2 (KH Domain Containing, RNA Binding, Signal Transduction Associated 2 (KHDRBS2))

Alternative Name: KHDRBS2

Background: KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces a
Alias Symbols: FLJ38664, MGC26664, SLM-1, SLM1, bA535F17.1
Protein Interaction Partner: HBZ, DOCK2, CIRBP, TYMSOS, LINC01018, KHDRBS2, ZFC3H1, CATSPER1, YTHDC1, PRR3, NABP1, AEN, NCOA5, NPDC1, RBMX, PRPF31, CHTOP, HNRNPR, MTA1, TYK2, SULT1A3, SPG7, SDCBP, RBM3, PTK6, UBC, KHDRBS3, HNRNPK, LYN, HNRNPC, HNRNPA2B1, HNRNPA1, FGG, FGB, FGA, DSG1,
Protein Size: 349

Molecular Weight: 39 kDa

Gene ID: 202559

NCBI Accession: NM_152688, NP_689901

UniProt: Q5VWX1