Fas Apoptotic Inhibitory Molecule (FAIM) (N-Term) antibody

Details for Product No. ABIN503894
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Antigen
Synonyms FAIM, faim, FAIM1, EG623459
Epitope
N-Term
(13), (8), (8), (3), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Xenopus laevis, Cow (Bovine), Dog (Canine), Zebrafish (Danio rerio), Human
(50), (31), (23), (15), (11), (11), (11)
Host
Rabbit
(43), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(41), (23), (9), (9), (4)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN503894
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human FAIM
Sequence MTDLVAVWDV ALSDGVHKIE FEHGTTSGKR VVYVDGKEEI RKEWMFKLVG
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Zebrafish : 80 %
Characteristics This is a rabbit polyclonal antibody against FAIM. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name FAIM
Background FAIM plays a role as an inducible effector molecule that mediates Fas resistance produced by surface Ig engagement in B cells.
Molecular Weight 24 kDa
Gene ID 55179
NCBI Accession NM_001033030, NP_001028202
UniProt Q9NVQ4
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 213 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Fas Apoptotic Inhibitory Molecule (FAIM) (N-Term) antibody WB Suggested Anti-FAIM Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
anti-Fas Apoptotic Inhibitory Molecule (FAIM) (N-Term) antibody (2) Immunohistochemistry with Thymus tissue at an antibody concentration of 5µg/ml using anti-FAIM antibody (ARP56237_P050)
Background publications Segura, Sole, Pascual et al.: "The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 42, pp. 11228-41, 2007 (PubMed).

Validation Images
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