PRKAR1B antibody (Middle Region)

Catalog No. ABIN503962

This Rabbit Polyclonal antibody specifically detects PRKAR1B in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit and Sheep.

Quick Overview for PRKAR1B antibody (Middle Region) (ABIN503962)

Target: PRKAR1B (Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKAR1B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRKAR1B Antibody

Binding Specificity: Middle Region

Sequence: LNRPRAATVV ARGPLKCVKL DRPRFERVLG PCSEILKRNI QRYNSFISLT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Sheep: 85%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PRKAR1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRKAR1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 381 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRKAR1B

Target: PRKAR1B (Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B))

Alternative Name: PRKAR1B

Background: Cyclic AMP-dependent protein kinase A (PKA) is an essential enzyme in the signaling pathway of the second messenger cAMP. Through phosphorylation of target proteins, PKA controls many biochemical events in the cell including regulation of metabolism, ion
Alias Symbols: PRKAR1
Protein Interaction Partner: UBC, DUS3L, THG1L, EEF2K, CALU, PRKACB, PRKACA, Dlg4, CUL3, WNK1, EGFR, PPP1R9A, WRN, SMAD3, AKAP1, SMAD4, PRKAR1A, PRKAR1B,
Protein Size: 381

Molecular Weight: 43 kDa

Gene ID: 5575

NCBI Accession: NM_002735, NP_002726

UniProt: P31321

Pathways: Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma