NOP58 antibody (Middle Region)

Catalog No. ABIN504082

This Rabbit Polyclonal antibody specifically detects NOP58 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit and Pigand has been mentioned in 1 publication.

Quick Overview for NOP58 antibody (Middle Region) (ABIN504082)

Target: NOP58 (NOP58 Ribonucleoprotein (NOP58))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOP58 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NOP58 Antibody

Binding Specificity: Middle Region

Sequence: LRTLEDRGIR KISGTGKALA KTEKYEHKSE VKTYDPSGDS TLPTCSKKRK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NOP5/NOP58. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NOP5/NOP58

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 529 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NOP58 antibody (ABIN504082)

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Target Details for NOP58

Target: NOP58 (NOP58 Ribonucleoprotein (NOP58))

Alternative Name: NOP5

Background: NOP58 is required for 60S ribosomal subunit biogenesis
Alias Symbols: HSPC120, NOP5, NOP5/NOP58
Protein Interaction Partner: UBC, SUMO2, SUMO3, SUMO1, SUZ12, EED, RNF2, BMI1, rev, CDK11A, CDK15, CDK20, TARDBP, FN1, ESR1, CSNK2A1, WHSC1, RPLP0P6, FTSJ3, NIFK, NOC4L, NHP2, GNL3, RSL1D1, NCSTN, BOP1, RRS1, EBNA1BP2, UTP14A, NOP56, NOLC1, PRPF3, SART1, U2AF1, RPS24, RPS15A, RPS14,
Protein Size: 529

Molecular Weight: 59 kDa

Gene ID: 51602

NCBI Accession: NM_015920, NP_057018

UniProt: Q9Y2X3

Pathways: Protein targeting to Nucleus