Thrombopoietin (THPO) antibody
| Antigen |
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| Synonyms |
ML, TPO, MGDF, MKCSF, MPLLG, MGC163194, Ml, Tpo, Mgdf, Tpo1, Tpo2, Tpo3, Tpo4, Mpllg, THPO, tpo, LOC100231762 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Conjugate
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Biotin (9), FITC (5), HRP (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Application
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ELISA (54), Western Blotting (WB) (53), Flow Cytometry (FACS) (16), Immunofluorescence (IF) (15), ELISA (Detection) (5), Immunocytochemistry (ICC) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Functional Studies (Func) (2), Neutralization (Neut) (2), Blocking Antibody (Inhibition) (1), Blocking Antibody (Inhibition) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
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| Catalog no. |
ABIN504523 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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Thrombopoietin
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Gene ID
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THPO
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UniProt
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P40225
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Immunogen
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The immunogen for anti-THPO antibody: synthetic peptide directed towards the middle region of human THPO
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Sequence
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HELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQP GYSPSPTHPP
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Cross-Reactivity
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Human
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-THPO antibody concentration is 1 mg/ml.
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Description
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Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. THPO is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Characteristics
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Antigen Size: 353 amino acids
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Molecular Weight
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35kDa
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Application Notes
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WB Suggested Anti-THPO Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Research Area
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Cancer, Cell Cycle, Hormones
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Restrictions
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For Research Use only
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Product
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Baker, Su, Hsu et al.: "Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats." in: Cardiovascular research, Vol. 77, Issue 1, pp. 44-53, 2008 (PubMed).
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Alternatives for antigen "Thrombopoietin (THPO)", type "Antibodies"
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Hosts
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Rabbit (38), Sheep (21), Mouse (12), Goat (10)
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Reactivities
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Human (54), Mouse (Murine) (40), Rat (Rattus) (18), Dog (Canine) (1)
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Applications
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ELISA (54), Western Blotting (WB) (53), Flow Cytometry (FACS) (16), Immunofluorescence (IF) (15), ELISA (Detection) (5), Immunocytochemistry (ICC) (5), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Functional Studies (Func) (2), Neutralization (Neut) (2), Blocking Antibody (Inhibition) (1), Blocking Antibody (Inhibition) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1), Immunoprecipitation (IP) (1)
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Conjugates
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Biotin (9), FITC (5), HRP (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
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Epitopes
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AA 14-29 (3), AA 244-277 (3), C-Term (2), Internal Region (2), AA 35-50 (1), Center (1)
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Alternatives 
2013 BioMed Central Research Awards
