TCL1A antibody (N-Term)
Quick Overview for TCL1A antibody (N-Term) (ABIN504546)
Target
See all TCL1A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL
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Predicted Reactivity
- Human: 100%
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Characteristics
- This is a rabbit polyclonal antibody against TCL1A. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TCL1A
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 114 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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Alternative Name
- TCL1A
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Background
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TCL1A can enhance the phosphorylation and activation of AKT1, AKT2 and AKT3,promote nuclear translocation of AKT1,enhance cell proliferation, stabilize mitochondrial membrane potential and promote cell survival.
Alias Symbols: TCL1
Protein Interaction Partner: TXLNA, TXLNB, ALS2CR12, CARD9, PRTFDC1, CEP55, LSM3, TTC33, WDR47, CALCOCO2, CADPS, TCL1A, TRAF1, TP53BP2, TCF4, GOLGA2, DNMT3A, AKT1, JUNB, JUN, FOS, EP300, ATM, HIST3H2A, AKT3, AKT2,
Protein Size: 114 -
Molecular Weight
- 13 kDa
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Gene ID
- 8115
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NCBI Accession
- NM_021966, NP_068801
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UniProt
- P56279
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Pathways
- Stem Cell Maintenance
Target
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