EIF2C3 antibody (N-Term)

Catalog No. ABIN504548

The Rabbit Polyclonal anti-EIF2C3 antibody has been validated for WB. It is suitable to detect EIF2C3 in samples from Human, Mouse, Cow, Rat, Zebrafish (Danio rerio), Dog, Horse, Pig, Rabbit and Guinea Pig.

Quick Overview for EIF2C3 antibody (N-Term) (ABIN504548)

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Reactivity: Human, Mouse, Cow, Rat, Zebrafish (Danio rerio), Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2C3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EIF2C3 Antibody

Binding Specificity: N-Term

Sequence: MCEVLDIHNI DEQPRPLTDS HRVKFTKEIK GLKVEVTHCG TMRRKYRVCN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against EIF2C3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2C3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 626 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF2C3

Target: EIF2C3 (Eukaryotic Translation Initiation Factor 2C3 (EIF2C3))

Alternative Name: EIF2C3

Background: EIF2C3 is a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is
Alias Symbols: AGO3, FLJ12765, MGC86946, EIF2C3
Protein Interaction Partner: AGO4, TNRC6C, TNRC6A, AGO2, AGO1, ZNF346, DICER1, TNRC6B, TARBP2, PRKAR1A, ATP6V0D2, UBC, SLC22A2, BDNF, ATP4B, CAND1, CUL3, CUL5, AGO3, ATAD3B, WDR77, PSPC1, QPCTL, OTUD4, SF3B6, EIF3L, PRPF31, SUN2, PHB2, STK38, SPIN1, RUVBL2, IPO8, TAB1, PRMT5, TUBB4B,
Protein Size: 626

Molecular Weight: 69 kDa

Gene ID: 192669

NCBI Accession: NM_177422, NP_803171

UniProt: B1ALI0

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway