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Myocyte Enhancer Factor 2C (MEF2C) antibody

Antigen

Myocyte Enhancer Factor 2C (MEF2C)
Synonyms mef2c, MGC64184, zgc:64184, zgc:85726, id:ibd5026, wu:fc05b06, XMEF2C, MGC80986, MEF2C, RGD1563119, Mef2, AV011172, 5430401D19Rik, 9930028G15Rik, MGC137710, si:ch211-202e12.2, DKFZp459O232
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Dog (Canine), Human, Rat (Rattus), Mouse (Murine), Pig (Porcine), Zebrafish, Chicken
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB)
1 reference available
Catalog no. ABIN504660
Quantity 50 µg  (Variants)
Price 317.90 $   Plus shipping costs $45.00
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anti-Myocyte Enhancer Factor 2C (MEF2C) antibody

Additional Information
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Alternative name MEF2C
Gene ID MEF2C
UniProt Q06413
Immunogen The immunogen for anti-MEF2C antibody: synthetic peptide directed towards the middle region of human MEF2C
Sequence PPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPP RDRTTTPSRY
Cross-Reactivity Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Format Lyophilized
Reconstitution Add 50 µl of distilled water. Final anti-MEF2C antibody concentration is 1 mg/ml.
Description MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Characteristics Antigen Size: 473 amino acids
Molecular Weight 51kDa

Application Details
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Application Notes WB Suggested Anti-MEF2C Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysate.
Purification Affinity Purified
Buffer PBS
Storage (Long Term) For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Storage (Short Term) Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
Research Area Cardiovascular, Hypertrophy, Cardiogenesis, Transcription Factors
Restrictions For Research Use only

Publications
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Product Nagel, Meyer, Quentmeier et al.: "MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines." in: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, Vol. 22, Issue 3, pp. 600-7, 2008 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Myocyte Enhancer Factor 2C (MEF2C)", type "Antibodies"
Hosts Rabbit (92), Mouse (19), Goat (1)
Reactivities Human (111), Mouse (Murine) (59), Rat (Rattus) (57), Pig (Porcine) (33), Dog (Canine) (31), Cow (Bovine) (29), Chicken (25), Sheep (Ovine) (24), Rabbit (4), Cat (Feline) (1), Xenopus laevis (1), Zebrafish (1)
Applications ELISA (55), Western Blotting (WB) (53), Immunofluorescence (IF) (50), Immunohistochemistry (IHC) (28), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (11), Flow Cytometry (FACS) (7), Dot Blot (Dot) (5), Immunoprecipitation (IP) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (6), Alexa Fluor 488 (6), Alexa Fluor 555 (6), Alexa Fluor 647 (6), PE,Cy5.5 (6), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pSer387 (8), pSer396 (8), pSer59 (7), pThr20 (7), pThr300 (6), C-Term (2), Ser387 (2), Ser396 (2), Ser59 (2), Thr300 (2), AA 1-125 (1), Internal Region (1), N-Term (1), pSer30,pTyr29 (1)