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Details for Product No. ABIN504660

Myocyte Enhancer Factor 2C (MEF2C) antibody

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Antigen
Synonyms id:ibd5026, mef2c, wu:fc05b06, zgc:64184, zgc:85726, XMEF2C, RGD1563119, C5DELq14.3, DEL5q14.3, Mef2, AV011172, 5430401D19Rik, 9930028G15Rik, MEF2C, si:ch211-202e12.2
Reactivity
»Alternatives Dog (Canine), Human, Rat (Rattus), Mouse (Murine), Pig (Porcine), Zebrafish, Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN504660
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-MEF2C antibody: synthetic peptide directed towards the middle region of human MEF2C
Sequence PPSALSQLGACTSTHLSQSSNLSLPSTQSLNIKSEPVSPP RDRTTTPSRY
Cross-Reactivity Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
Predicted Reactivity Dog : 100%, Horse : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rabbit : 100%, Rat : 100%, Zebrafish : 100%
Characteristics Antigen Size: 473 amino acids
Purification Affinity Purified
Alternative Name MEF2C
Background MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Molecular Weight 51kDa
Gene ID MEF2C
UniProt Q06413
Research Area Cardiovascular, Hypertrophy, Cardiogenesis, Transcription Factors
Application Notes WB Suggested Anti-MEF2C Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysate.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µl of distilled water
Buffer Final anti-MEF2C antibody concentration is 1 mg/ml.
Storage 4 °C
Storage Comment Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen. For longer periods of storage, store at -20°C
Background publications Nagel, Meyer, Quentmeier et al.: "MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines." in: Leukemia, Vol. 22, Issue 3, pp. 600-7, 2008 (PubMed).

Alternatives for antigen "Myocyte Enhancer Factor 2C (MEF2C)", type "Antibodies"
Hosts (148), (24), (1)
Reactivities (172), (100), (78), (73), (61), (49), (48), (1), (1)
Applications (84), (63), (60), (38), (36), (17), (11), (10), (2), (2), (1)
Conjugates (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6)
Epitopes (25), (21), (17), (17), (14), (4), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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