GTF2H2 antibody (Middle Region)
Quick Overview for GTF2H2 antibody (Middle Region) (ABIN504667)
Target
See all GTF2H2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- HHLFPLDAFQ EIPLEEYNGE RFCYGCQGEL KDQHVYVCAV CQNVFCVDCD
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Cross-Reactivity
- Human
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Predicted Reactivity
- Dog: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Zebrafish: 85%
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Characteristics
- This is a rabbit polyclonal antibody against GTF2H2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GTF2H2
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Application Notes
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WB Suggested Anti-GTF2H2 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. -
Comment
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Antigen size: 395 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))
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Alternative Name
- GTF2H2 / BTF2P44
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Background
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GTF2H2 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence hav
Alias Symbols: BTF2, BTF2P44, MGC102806, T-BTF2P44, TFIIH, p44
Protein Interaction Partner: UBC, CDK7, GTF2H5, GTF2H1, SRA1, GTF2H4, GTF2H3, UBD, COPS2, ERCC3, ERCC8, ERCC2, AR, MNAT1, CCNH,
Protein Size: 395 -
Molecular Weight
- 44 kDa
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Gene ID
- 2966
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NCBI Accession
- NM_001515, NP_001506
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UniProt
- Q13888
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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