HEYL antibody (AA 221-327)

Catalog No. ABIN525732

Cited in 1 publication. The Mouse Monoclonal anti-HEYL antibody (Clone 1F6) (ABIN525732) specifically detects HEYL in WB, ELISA, IF and IHC (p). The antibody is reactive with Human samples.

Quick Overview for HEYL antibody (AA 221-327) (ABIN525732)

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HEYL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 1F6

Product Details anti-HEYL Antibody

Binding Specificity: AA 221-327

Purpose: Mouse monoclonal antibody raised against a partial recombinant HEYL.

Sequence: PLRRATGIIL PARRNVLPSR GASSTRRARP LERPATPVPV APSSRAARSS HIAPLLQSSS PTPPGPTGSA AYVAVPTPNS SSPGPAGRPA GAMLYHSWVS EITEIGA

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: HEYL (NP_055386, 221 a.a. ~ 327 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-HEYL antibody (ABIN525732)

Lavery, Villaronga, Walker, Patel, Belandia, Bevan: "Repression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectors." in: The Journal of biological chemistry, Vol. 286, Issue 20, pp. 17796-808, (2011) (PubMed).

Target Details for HEYL

Target: HEYL (Hairy/enhancer-of-Split Related with YRPW Motif-Like (HEYL))

Alternative Name: HEYL

Background: Full Gene Name: hairy/enhancer-of-split related with YRPW motif-like
Synonyms: HRT3,MGC12623,bHLHb33

Gene ID: 26508

NCBI Accession: NM_014571

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling