CHMP3 antibody (Internal Region)

Catalog No. ABIN559706

The Rabbit Polyclonal anti-CHMP3 antibody (ABIN559706) specifically detects CHMP3 in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for CHMP3 antibody (Internal Region) (ABIN559706)

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CHMP3 Antibody

Binding Specificity: Internal Region

Specificity: Reacts with human 25 kDa hVps24

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): May cross-react with protein from mouse, rat and other species due to sequence homology.

Purification: Antiserum

Immunogen: Synthetic peptide derived from internal domain of human Vps24 protein

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC1:200 - 1:2000 WB1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for CHMP3

Target: CHMP3 (Charged Multivesicular Body Protein 3 (CHMP3))

Alternative Name: Charged Multivesicular Body Protein 3

Background: Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids.

Gene ID: 51652

UniProt: Q9Y3E7