ATP6V1B2 antibody (AA 1-511)

Catalog No. ABIN560004

Cited in 2+ publications. The Mouse Monoclonal anti-ATP6V1B2 antibody (Clone M1) (ABIN560004) specifically detects ATP6V1B2 in ELISA. The antibody is reactive with Human samples.

Quick Overview for ATP6V1B2 antibody (AA 1-511) (ABIN560004)

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATP6V1B2 antibody is un-conjugated

Application: ELISA

Clone: M1

Product Details anti-ATP6V1B2 Antibody

Binding Specificity: AA 1-511

Purpose: Mouse monoclonal antibody raised against a full length recombinant ATP6V1B2.

Sequence: MALRAMRGIV NGAAPELPVP TGGPAVGARE QALAVSRNYL SQPRLTYKTV SGVNGPLVIL DHVKFPRYAE IVHLTLPDGT KRSGQVLEVS GSKAVVQVFE GTSGIDAKKT SCEFTGDILR TPVSEDMLGR VFNGSGKPID RGPVVLAEDF LDIMGQPINP QCRIYPEEMI QTGISAIDGM NSIARGQKIP IFSAAGLPHN EIAAQICRQA GLVKKSKDVV DYSEENFAIV FAAMGVNMET ARFFKSDFEE NGSMDNVCLF LNLANDPTIE RIITPRLALT TAEFLAYQCE KHVLVILTDM SSYAEALREV SAAREEVPGR RGFPGYMYTD LATIYERAGR VEGRNGSITQ IPILTMPNDD ITHPIPDLTG YITEGQIYVD RQLHNRQIYP PINVLPSLSR LMKSAIGEGM TRKDHADVSN QLYACYAIGK DVQAMKAVVG EEALTSDDLL YLEFLQKFER NFIAQGPYEN RTVFETLDIG WQLLRIFPKE MLKRIPQSTL SEFYPRDSAK H

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ATP6V1B2 (AAH03100, 1 a.a. ~ 511 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ATP6V1B2 antibody (ABIN560004)

Eriksson, Joosten, Roberg, Ollinger: "The histone deacetylase inhibitor trichostatin A reduces lysosomal pH and enhances cisplatin-induced apoptosis." in: Experimental cell research, Vol. 319, Issue 1, pp. 12-20, (2012) (PubMed).

Nilsson, Roberg, Grafström, Ollinger: "Intrinsic differences in cisplatin sensitivity of head and neck cancer cell lines: Correlation to lysosomal pH." in: Head & neck, Vol. 32, Issue 9, pp. 1185-94, (2010) (PubMed).

Target Details for ATP6V1B2

Target: ATP6V1B2 (ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2))

Alternative Name: ATP6V1B2

Background: Full Gene Name: ATPase, H+ transporting, lysosomal 56/58 kDa, V1 subunit B2
Synonyms: ATP6B1B2,ATP6B2,HO57,VATB,VPP3,Vma2

Gene ID: 526

Pathways: Transition Metal Ion Homeostasis, Proton Transport