AKR1C4 antibody (AA 1-323)

Catalog No. ABIN560358

Cited in 1 publication. The Mouse Monoclonal anti-AKR1C4 antibody (Clone 2C11) (ABIN560358) specifically detects AKR1C4 in WB, ELISA, IHC (p) and IF. The antibody is reactive with Human samples.

Quick Overview for AKR1C4 antibody (AA 1-323) (ABIN560358)

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AKR1C4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: 2C11

Product Details anti-AKR1C4 Antibody

Binding Specificity: AA 1-323

Purpose: Mouse monoclonal antibody raised against a full length recombinant AKR1C4.

Sequence: MDPKYQRVEL NDGHFMPVLG FGTYAPPEVP RNRAVEVTKL AIEAGFRHID SAYLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCTFF QPQMVQPALE SSLKKLQLDY VDLYLLHFPM ALKPGETPLP KDENGKVIFD TVDLSATWEV MEKCKDAGLA KSIGVSNFNY RQLEMILNKP GLKYKPVCNQ VECHPYLNQS KLLDFCKSKD IVLVAHSALG TQRHKLWVDP NSPVLLEDPV LCALAKKHKR TPALIALRYQ LQRGVVVLAK SYNEQRIREN IQVFEFQLTS EDMKVLDGLN RNYRYVVMDF LMDHPDYPFS DEY

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: AKR1C4 (AAH20744, 1 a.a. ~ 323 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-AKR1C4 antibody (ABIN560358)

Stayrook, Rogers, Savkur, Wang, Su, Varga, Bu, Wei, Nagpal, Liu, Burris: "Regulation of human 3 alpha-hydroxysteroid dehydrogenase (AKR1C4) expression by the liver X receptor alpha." in: Molecular pharmacology, Vol. 73, Issue 2, pp. 607-12, (2008) (PubMed).

Target Details for AKR1C4

Target: AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))

Alternative Name: AKR1C4

Background: Full Gene Name: aldo-keto reductase family 1, member C4 (chlordecone reductase, 3-alpha hydroxysteroid dehydrogenase, type I, dihydrodiol dehydrogenase 4)
Synonyms: 3-alpha-HSD,C11,CDR,CHDR,DD4,HAKRA,MGC22581

Gene ID: 1109

Pathways: Steroid Hormone Biosynthesis