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Details for Product No. ABIN561520

Interferon Regulatory Factor 1 (IRF1) (AA 216-325) antibody

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Antigen
Synonyms MAR, IRF-1, Irf-1, AU020929, irf1, zgc:136945, IRF1, irf11, zgc:103566
Epitope
»Alternatives AA 216-325
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), ELISA
Pubmed 7 references available
Catalog no. ABIN561520
Quantity 100 µg
Price
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Immunogen IRF1 (NP_002189, 216 a.a. ~ 325 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: PMPSTSEATTDEDEEGKLPE DIMKLLEQSEWQPTNVDGKG YLLNEPGVQPTSVYGDFSCK EEPEIDSPGGDIGLSLQRVF TDLKNMDATWLDSLLTPVRL PSIQAIPCAP
Clone 2E4
Isotype IgG2a kappa
Characteristics Mouse monoclonal antibody raised against a partial recombinant IRF1.
Alternative Name IRF1
Background Gene: interferon regulatory factor 1
Synonyms: IRF-1, MAR
Gene ID 3659
NCBI Accession NM_002198, NP_002189
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Application specialization: Cell lysate, Recombinant protein
Restrictions For Research Use only
Buffer 1x PBS, pH 7.2
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Product cited in: Ye, Lista, Lo Coco et al.: "Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma." in: Science (New York, N.Y.), Vol. 262, Issue 5134, pp. 747-50, 1993 (PubMed).

Steffen, MacKay, Kerr et al.: "Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4." in: Cell, Vol. 133, Issue 2, pp. 292-302, 2008 (PubMed).

Fazilleau, McHeyzer-Williams, Rosen et al.: "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding." in: Nature immunology, Vol. 10, Issue 4, pp. 375-84, 2009 (PubMed).

Nurieva, Chung, Martinez et al.: "Bcl6 mediates the development of T follicular helper cells." in: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1001-5, 2009 (PubMed).

Choi, Kageyama, Eto et al.: "ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6." in: Immunity, Vol. 34, Issue 6, pp. 932-46, 2011 (PubMed).

Baumjohann, Okada, Ansel: "Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2089-92, 2011 (PubMed).

Bartlett, Slater, Glanville et al.: "Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus." in: EMBO molecular medicine, Vol. 4, Issue 12, pp. 1244-60, 2012 (PubMed).

Alternatives for antigen "Interferon Regulatory Factor 1 (IRF1)", type "Antibodies"
Hosts (34), (13), (1)
Reactivities (42), (19), (14), (14), (14), (14), (1), (1)
Applications (34), (11), (10), (4), (2), (2), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (4), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1)
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