RDH5 antibody (AA 181-280)

Catalog No. ABIN562619

There are 3+ publications for this product available. The Mouse Polyclonal anti-RDH5 antibody is suitable to detect RDH5 in samples from Human. It has been validated for ELISA and WB.

Quick Overview for RDH5 antibody (AA 181-280) (ABIN562619)

Target: RDH5 (Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5))

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This RDH5 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-RDH5 Antibody

Binding Specificity: AA 181-280

Purpose: Mouse polyclonal antibody raised against a partial recombinant RDH5.

Sequence: GLEAFSDSLR RDVAHFGIRV SIVEPGFFRT PVTNLESLEK TLQACWARLP PATQAHYGGA FLTKYLKMQQ RIMNLICDPD LTKVSRCLEH ALTARHPRTR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: RDH5 (AAH28298, 181 a.a. ~ 280 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-RDH5 antibody (ABIN562619)

Fokidis, Yieng Chin, Ho, Adomat, Soma, Fazli, Nip, Cox, Krystal, Zoubeidi, Tomlinson Guns: "A low carbohydrate, high protein diet suppresses intratumoral androgen synthesis and slows castration-resistant prostate tumor growth in mice." in: The Journal of steroid biochemistry and molecular biology, Vol. 150, pp. 35-45, (2015) (PubMed).

Lubik, Gunter, Hendy, Locke, Adomat, Thompson, Herington, Gleave, Pollak, Nelson: "Insulin increases de novo steroidogenesis in prostate cancer cells." in: Cancer research, Vol. 71, Issue 17, pp. 5754-64, (2011) (PubMed).

Locke, Guns, Lubik, Adomat, Hendy, Wood, Ettinger, Gleave, Nelson: "Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer." in: Cancer research, Vol. 68, Issue 15, pp. 6407-15, (2008) (PubMed).

Target Details for RDH5

Target: RDH5 (Retinol Dehydrogenase 5 (11-Cis/9-Cis) (RDH5))

Alternative Name: RDH5

Background: Full Gene Name: retinol dehydrogenase 5 (11-cis/9-cis)
Synonyms: FLJ39337,FLJ97089,HSD17B9,RDH1,SDR9C5

Gene ID: 5959