ZCCHC11 antibody (C-Term)

Catalog No. ABIN568022

The Goat Polyclonal anti-ZCCHC11 antibody is suitable to detect ZCCHC11 in samples from Human, Mouse, Rat, Dog and Cow. It has been validated for IHC (p) and EIA.

Quick Overview for ZCCHC11 antibody (C-Term) (ABIN568022)

Target: ZCCHC11 (Zinc Finger, CCHC Domain Containing 11 (ZCCHC11))

Reactivity: Human, Mouse, Rat, Dog, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This ZCCHC11 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-ZCCHC11 Antibody

Binding Specificity: C-Term

Sequence: RERCPHPPRG NVSE

Specificity: This antibody is expected to recognize all 3 reported isoforms.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog) and Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from the C Terminus of the protein according to NP_001009881.1, NP_056084.1 and NP_001009882.1. Genename: ZCCHC11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ZCCHC11

Target: ZCCHC11 (Zinc Finger, CCHC Domain Containing 11 (ZCCHC11))

Alternative Name: ZCCHC11

Background: ZCH11 is known to direct cytokine expression by uridylating cytokine-targeting miRNAs. ZCH11 is a ribonucleotidyltransferase with a preference for uridine and is essential for maintaining the poly(A) tail length and stability of transcripts for interleukin-6 (IL-6), plus other specific cytokines.Synonyms: KIAA0191, Zinc finger CCHC domain-containing protein 11

Gene ID: 23318

NCBI Accession: NP_001009881

UniProt: Q5TAX3

Pathways: Stem Cell Maintenance