Oxalate Decarboxylase antibody (Biotin)
Quick Overview for Oxalate Decarboxylase antibody (Biotin) (ABIN568343)
Target
Reactivity
Host
Clonality
Conjugate
Application
-
-
Specificity
- Oxalate Decarboxylase from Aspergillus species. The reagents were evaluated for potency, purity and specificity using most or all of the following techniques: Immunoelectrophoresis, Cross-Immunoelectrophoresis, Single Radial Immunodiffusion (Ouchterlony), block titration, ELISA, Immunoblotting and enzyme inhibition. Cross-reactivities against enzymes of other sources may occur but have not been determined.
-
Characteristics
- Molar Ratio: Biotin/IgG ~ 4.6
-
Purification
- Ammonium Sulphate Precipitation and Ion Exchange Chromatography
-
Immunogen
- Oxalate Decarboxylase isolated and purified from Aspergillus species. Freund’s complete adjuvant is used in the first step of the immunization procedure.
-
Isotype
- IgG
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Reconstitution
- Restore by adding 1.0 mL of sterile distilled water
-
Concentration
- 10 mg/mL
-
Buffer
- PBS, pH 7.2 without preservatives and foreign proteins
-
Preservative
- Without preservative
-
Storage
- 4 °C/-20 °C
-
Storage Comment
- Store the antibody lyophilized at 2-8 °C and reconstituted at 2-8 °C for one week or (in aliquots) at -20 °C for longer. If a slight precipitation occurs upon storage, this should be removed by centrifugation.
-
-
- Oxalate Decarboxylase
-
Background
- Oxalates in animals including humans originate mostly from the diet, especially through ingestion of leafy vegetables and other plant parts. The catabolic pathway of oxalic acid is present in bacteria, fungi, and plants but not in vertebrates. Therefore, management of oxalate in humans is very important because of the absence of any enzyme system that can degrade oxalate. Excess ingestion of oxalate leads to an acute oxalate toxicity, which can result in a variety of disorders including renal failure and urolithiasis (Curhan 1997).Synonyms: OXDC, Oxalate Carboxy-lyase
-
Gene ID
- 3513167
-
NCBI Accession
- XP_755793
-
UniProt
- Q4X060
Target
-