GNB3 antibody (Internal Region)

Catalog No. ABIN569636

Product Details anti-GNB3 Antibody

Target: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Binding Specificity: Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This GNB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: SGHDNRVSCL GVT

Specificity: This antibody is expected to recognize GNB3 and GNB4 (NP_002066.1 and NP_067642.1).

Cross-Reactivity (Details): Species reactivity (tested):Human.
Also reacts to: GNB4

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002066.1, NP_067642.1. Genename: GNB3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GNB3

Target: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Alternative Name: Transducin beta Chain 3 (GNB3) (GNB3 Products)

Synonyms: Gnb-3 antibody, MGC68913 antibody, MGC130764 antibody, gnb3 antibody, zgc:73058 antibody, zgc:77780 antibody, wu:fk54b04 antibody, gnb3l antibody, zgc:92641 antibody, G protein subunit beta 3 antibody, guanine nucleotide binding protein (G protein), beta 3 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog antibody, guanine nucleotide binding protein (G protein), beta polypeptide 3b antibody, guanine nucleotide binding protein (G protein), beta polypeptide 3a antibody, GNB3 antibody, Gnb3 antibody, gnb3.S antibody, gnb3b antibody, gnb3a antibody

Background: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.Synonyms: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

Molecular Weight: 37.2kDa (NP_002066.1).

Gene ID: 2784

NCBI Accession: NP_002066

UniProt: P16520

Pathways: Peptide Hormone Metabolism, Myometrial Relaxation and Contraction