DR3/LARD antibody (Biotin)

Catalog No. ABIN610236

Cited in 2+ publications. The Biotin-conjugated Mouse Monoclonal anti-DR3/LARD antibody (Clone ANC2D12) (ABIN610236) specifically detects DR3/LARD in ELISA. The antibody is reactive with Human samples.

Quick Overview for DR3/LARD antibody (Biotin) (ABIN610236)

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This DR3/LARD antibody is conjugated to Biotin

Application: ELISA

Clone: ANC2D12

Product Details anti-DR3/LARD Antibody (Biotin)

Specificity: Clone ANC2D12 binds specifically to recombinant DR3 in EIA, but does not inhibit DR3 binding to TL1A.

Purification: Protein A purified

Immunogen: Human HPB-MLT cells, recombinant human CD278(ICOS)-muIg.

Isotype: IgG1 kappa

Application Details

Application Notes: Approved: ELISA

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-DR3/LARD antibody (Biotin) (ABIN610236)

Tworkowski, Salghetti, Tansey: "Stable and unstable pools of Myc protein exist in human cells." in: Oncogene, Vol. 21, Issue 55, pp. 8515-20, (2002) (PubMed).

Downey, Butler, Tapper, Fialkow, Saltiel, Rubin, Grinstein: "Importance of MEK in neutrophil microbicidal responsiveness." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 1, pp. 434-43, (1998) (PubMed).

Target Details for DR3/LARD

Target: DR3/LARD (TNFRSF25) (Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))

Alternative Name: TNFRSF25 / DR3

Background: Name/Gene ID: TNFRSF25
Family: TNF Receptor

Synonyms: TNFRSF25, APO-3, APO3, DDR3, Death receptor 3, DR3, Death receptor beta, LARD, Protein WSL, TR3, WSL, WSL-1, WSL-LR, Apoptosis inducing receptor, TNFRSF12, WSL1, Protein WSL-1, TRAMP

Gene ID: 8718

UniProt: Q93038

Pathways: Apoptosis