TNFRSF18 antibody (Biotin)

Catalog No. ABIN610416

Cited in 1 publication. The Biotin-conjugated Mouse Monoclonal anti-TNFRSF18 antibody (Clone ANC5E3) (ABIN610416) specifically detects TNFRSF18 in FACS and ELISA. The antibody is reactive with Human samples.

Quick Overview for TNFRSF18 antibody (Biotin) (ABIN610416)

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF18 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), ELISA

Clone: ANC5E3

Product Details anti-TNFRSF18 Antibody (Biotin)

Specificity: Human GITR in EIA and on cell surface in FACS. Preincubation of the receptor with an excess of this mAb will block binding of recombinant GITR Ligand.

Purification: Protein A purified

Immunogen: Recombinant human GITR, PHA stimulated human PBL.

Type of Immunogen: Recombinant protein

Isotype: IgG3 kappa

Application Details

Application Notes: Approved: ELISA, Flo

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-TNFRSF18 antibody (Biotin) (ABIN610416)

Fallon, Moreau, Croft, Labib, Gu, Fon: "Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain." in: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 486-91, (2002) (PubMed).

Target Details for TNFRSF18

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Alternative Name: TNFRSF18 / GITR

Background: Name/Gene ID: TNFRSF18
Family: TNF Receptor

Synonyms: TNFRSF18, AITR, CD357, CD357 antigen, GITR, GITR-D

Gene ID: 8784

UniProt: Q9Y5U5

Pathways: Cancer Immune Checkpoints